Terminus is the campaign of my DnD group and has been running for over two years. We began it not too long after DnD 4th Edition released and have gone from starting level characters to level 16 world travelling heroes. I play Adah-Kah, a Nekhanj (based on the Dromite from previous editions) Avenger of the goddess Ioun.
To give a breif summary of the plot, each of the player characters is the lastor nearly last representative of their respective races. Adah-kah was found on the edge of a desert in the arms of a Nekhanj statue and adopted by a temple of Ioun. Over time, he trained in the teachings of Ioun and the ways of an Avenger. Being always different and ever a subject of study, Adah-kah learned to keep his appearance semi-obscured when in public. He also made it his goal to find his vanished people. Eventually he set out on excursions first to the desert, then the great library in the city of Span to see what he could discover.
Span is a city built on a bridge over a swift moving inland sea called the Scarring. The Scarring also refers to an event in the world's history in which magic users of the Dragonborn race very nearly destroyed the world and broke their continent in two. The Dragonborn had a magi-tech empire that crumbled after the Scarring, leaving a sole representative (the PC Sabriel). The Nekhanj previously warred with the Githyanki, but retreated suddenly and the Githyanki empire went into decline until their former slaves the Lizardfoll began to hunt them down mercilessly. It's possible the PC Vallo is the last Githyanki.
Once, the Warforged race were born at a great factory called the Forge, but the Forge is now missing and the Warcorged are shut down, save for the newly awakened PC, Meggido. It's possible that the Skeshuni, who later became unable to breed, may have had something to do with those events. Their final representative is the PC Sardis. The PCs ostensibly are working for the Watcher, a mysterious godlike being who typically does not interfere with the world but who has gathered this group to face a cataclysmic threat. The Watcher, on occasion, sends visions to the heroes which expand on their powers beyond the normal hero's. The PC's are occasionally aided by Grontonn, a Minotaur ship captain, his crew and a dog Vallo rescued named Kun Kun.
The PC's have helped re-form the Talminar Province, stop a vampire (twice because we avoided her the first time), shut down an army of false Warforged, released a Dragonborn lich (uhhhh...), awoken the lich's dragon ally (UHHHH...), rescued several towns, gathered a war effort against undead forces, crushed a gang called the Firehawks (Firehawks suck!), investigated mines and caves including an ancient Nekhanj city, found two pieces of a device which might save the world, discovered an invasion by Beholders, and most recently maybe, kinda sorta permanently collapsed a demi-plane used for rapid travel (oops!).
This session was focused on getting on to our next objective. We checked in with the folks we'd last worked with and discovered the trolls we'd fought/allied with were moving in to support the other races fighting the undead. The maybe-not-a-Succubus who'd accompanied us was turned over to Sardis' old university for investigation. And Sabriel, using Dragonborn directional senses that the Watcher may be tapping in to, directex the party into a forest to the southwest, quite near to Sardis' home. On the way we fought some assassin vines which put a severe hurting on the party (three or four of us were bloodied within a round and a half). Adah-kah did get a couple good shots in, as did everyone else, but it was a rather unpleasant fight overall.
We continued on riding our magic flying boars (because we're awesome) and came across a Treant (which we immediatelt redubbed an Ent), who told us about a corrupt "pink fleshy thing" (I forget his name) who is spreading kudzu-like Darkwood through the forest, which is increasing the population of plant mosters such as assassin vines. We continued on, flying over an encounter (yeah, our boars are awesome) and then finding overgrown Skeshuni ruins, actually the Skeshuni capital, where Vallo summoned up a guide to help us find the seat of governent. And I believe that's where we left off until next week.